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Prospective Cohort Study on the Impact of Immune-Related Adverse Events (irAEs) on Prognosis in Advanced Tumor Patients Treated with Immune Checkpoint Inhibitors

Prospective Cohort Study on the Impact of Immune-Related Adverse Events (irAEs) on Prognosis in Advanced Tumor Patients Treated with Immune Checkpoint Inhibitors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109877
Enrollment
Unknown
Registered
2025-09-26
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer and gastric

Interventions

group with Immune-related adverse events:Immune-related adverse events (irAEs) occurred.

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients were required to be at least 18 years of age at initiation of ICI therapy; 2. Malignant tumor cancer confirmed by histology or cytology; 3. Patients should receive at least one ICI, either alone or in combination with chemotherapy. 4. At the time of starting ICI, patients were classified as having stage IV disease according to TNM stage or medically documented inoperable stage III disease.

Exclusion criteria

Exclusion criteria: 1. Patients with a previous history of other malignancies were eligible if they had had another solid tumor and achieved a state of complete remission by surgery, radiotherapy, or other forms of combined therapy, with no evidence of recurrence or metastasis documented by medical records for more than 5 years since final treatment was completed. 2. Patients with mental disorders

Design outcomes

Primary

MeasureTime frame
1-year PFS rate;

Countries

China

Contacts

Public ContactWang Han

Fujian Medical University Union Hospital

wang_han2011@163.com+86 591 86218042

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026