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Evaluation of the early diagnostic and prognostic value of copeptin combining with point-of-care ultrasound in patients with acute dyspnea(pulmonary embolism)

Evaluation of the early diagnostic and prognostic value of copeptin combining with point-of-care ultrasound in patients with acute dyspnea(pulmonary embolism)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109859
Enrollment
Unknown
Registered
2025-09-25
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism

Interventions

Index test:1. Copeptin detection: Collect the residual blood samples from the patients' initial laboratory tests during their routine medical visits. 2. POCUS examination: Conducted within 24 hours of

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The patient is aged >= 18 years. 2. Acute dyspnea, chest pain, or other symptoms suggestive of pulmonary embolism. 3. Wells score > 4 or D-dimer level >= 500 ng/mL. 4. The patient agrees to comply with the requirements of this protocol, including follow-up and other related matters.

Exclusion criteria

Exclusion criteria: 1. A history of chronic pulmonary arterial hypertension or chronic pulmonary embolism (PE). 2. Acute myocardial infarction or heart failure. 3. Severe renal insufficiency, including patients with end-stage renal disease requiring dialysis. 4. Pregnant or breastfeeding patients. 5. Patients who have not undergone computed tomography pulmonary angiography (CTPA). 6. Patients who are unable to consent or unable to understand the informed consent document.

Design outcomes

Primary

MeasureTime frame
copeptin;Point-of-care ultrasound indicates thrombus in the right heart cavities or right ventricular dysfunction.;Accuracy;Sensitivity;Specificity;

Countries

China

Contacts

Public ContactWen Gao

China-Japan Friendship Hospital

kathygao102@aliyun.com+86 151 1008 1684

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026