Non-small cell lung cancer (NSCLC) with brain metastases
Conditions
Interventions
Observation group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Pathologically confirmed primary NSCLC patients with brain metastases; 3. Patients who have undergone stereotactic radiation therapy for intracranial lesions; 4. Patients receiving oral targeted therapy or intravenous immunotherapy; 5. PS score of 0-1.
Exclusion criteria
Exclusion criteria: 1. Patients whose radiation therapy plan is interrupted due to special reasons; 2. Patients without brain plain scan and enhanced MRI examination records after radiotherapy; 3. Patients who received stereotactic body radiation therapy after whole brain radiation therapy (WBRT); 4. Patients with double or multiple cancers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intracranial Progression-Free Survival, iPFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;intracranial Objective Response Rate, iORR;intracranial Disease Control Rate, iDCR;1-year intracranial Local Control Rate, 1-year iLCR; | — |
Countries
China
Contacts
Public ContactXu Shuangbing
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed