Severe aneurysmal subarachnoid hemorrhage
Conditions
Interventions
ICPm Group (ventricular type):None
No-ICP group (simple external drainage):None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Over 18 years old; 2. Diagnosis of subarachnoid hemorrhage caused by ruptured intracranial aneurysms through cranial CTA or DSA; 3. The Hunt-Hess grade at admission is greater than or equal to grade III; 4. Intracranial ruptured aneurysm occlusion (including interventional therapy or surgical treatment) should be performed within 24 hours after spider bleeding. 5. Patients who need to undergo intraventricular ICP implantation, external ventricular drainage tube (EVD) placement, ommaya implantation, or external lumbar cisterna drainage within 48 hours due to their condition for bloody cerebrospinal fluid drainage; 6. The patient's family members are aware of the research process and give informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclude subarachnoid hemorrhage caused by other reasons, including trauma, arteriovenous malformations, venous malformations, coagulopathy and other subarachnoid hemorrhage not caused by aneurysm rupture (negative angiography); 2. Intracranial aneurysm rupture and hemorrhage caused by infectious diseases; 3. Patients with a Hunt-Hess score < grade III; 4. Patients with severe comorbidities within 6 months prior to the onset of this disease, such as malignant tumors, drug-resistant heart disease, coagulation disorders, or severe failure of other organ functions; 5. Patients with spider blood who refuse to have their disease management information collected and used and/or refuse to receive follow-up visits; 6. Pregnant or lactating women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS Score (mRS>=4 is defined as a poor prognosis); | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications;Daily treatment intensity;GCS score at discharge;In-hospital mortality;ICP value or drainage height per hour; | — |
Countries
China
Contacts
Public ContactHu Jin
Huashan Hospital, Fudan University
Outcome results
None listed