Skip to content

Therapeutic Efficacy of Transcranial Direct Current Stimulation Combined with Neuromuscular Control Training in Patients with Chronic Lateral Ankle Instability

Therapeutic Efficacy of Transcranial Direct Current Stimulation Combined with Neuromuscular Control Training in Patients with Chronic Lateral Ankle Instability

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109812
Enrollment
Unknown
Registered
2025-09-25
Start date
2025-09-25
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Ankle Instability

Interventions

Control Group:Neuromuscular Control Training
Intervention Group:Transcranial Direct Current Stimulation Combined with Neuromuscular Control Training

Sponsors

Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. First ankle sprain occurred more than 12 months ago. 2. At least one episode of ankle sprain with swelling, pain, and temporary functional impairment within the past 3 months prior to enrollment. 3. Reported two or more episodes of "giving way" (a sensation of ankle instability during daily activities or sports, accompanied by fear of re-injury) in the 6 months preceding enrollment. 4. Cumberland Ankle Instability Questionnaire (CAIT) score <= 24.

Exclusion criteria

Exclusion criteria: 1. The patient has a history of lower limb trauma or surgery within the past 3 months 2. The patient has a history of chronic diseases, such as vestibular disorders, epilepsy, stroke and other neurological diseases, as well as a history of heart disease, cancer, mental disorders and migraines, etc. 3. Those who are pregnant, breastfeeding, or otherwise unable to cooperate to complete the test. 4. Patients with metal implants in their bodies who are not suitable for tDCS intervention and TMS examination

Design outcomes

Primary

MeasureTime frame
Isokinetic muscle test AND Proprioception test;

Secondary

MeasureTime frame
Balance test;Gait Analysis;Volar Stress Distribution Test;Surface electromyograph;Foot and Ankle Ability Measure;Safety evaluation (including event description, onset time, severity, duration, management, and outcome);Cortical motor excitability;

Countries

China

Contacts

Public ContactXiao Lu

Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)

xiaolu_5683@163.com+86 152 0213 1997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026