Carbapenem resistant Gram negative bacterial infections
Conditions
Interventions
Real-time antimicrobial resistance gene-guided therapy group:none
Empirical therapy group:none
Sponsors
Wuxi People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old; 2. The diagnosis of CRO infection in the patient is clear; Complete records of the patient's basic information and course of illness; And receive CZA treatment for = 3 days; 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. CRO colonization or contamination; 2. Allergic or intolerant to CZA; 3. Allergic or intolerant to CZA; 4. Patients with combined CRO bacteremia or sepsis; 5. In addition to infectious diseases, there are other diseases that affect the life of patients in a short term, such as pulmonary embolism, acute myocardial infarction, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 14 -day clinical therapy failure rate;21 -day clinical therapy failure rate;21- day microbial clearance failure rate; 60 -day mortality rate;adverse drug reaction/event rate; | — |
Countries
China
Contacts
Public ContactXiuhong Zhang
Wuxi People's Hospital
Outcome results
None listed