Elderly patients often have multiple underlying diseases and a poor compensatory capacity of the cardiovascular system. Insertion of a laryngeal mask can cause significant hemodynamic fluctuations and even lead to cardiovascular and cerebrovascular accidents during general anesthesia induction. Therefore, potent opioid analgesics are needed during anesthesia induction to suppress cardiovascular re
Conditions
Interventions
Experimental group:different doses of alfentanil
Sponsors
Hangzhou Third People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Surgical patients scheduled for laryngeal mask general anesthesia; 2.Age > 65 years old; 18.5<BMI<24kg/m^2; 3.ASA Class I or II;
Exclusion criteria
Exclusion criteria: 1.History of allergy to opioid analgesics; 2.Medical history of the nervous system; 3.History of gastroesophageal reflux; 4.Acute upper respiratory infection; 5.Long-term use of sedative drugs before the operation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiovascular reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reaction; | — |
Countries
China
Contacts
Public ContactJianming Yu
Hangzhou Third People's Hospital
Outcome results
None listed