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A Study on the Impact of Helicobacter pylori Infection on TSH Suppressive Therapy After Surgery for Papillary Thyroid Carcinoma

A Study on the Impact of Helicobacter pylori Infection on TSH Suppressive Therapy After Surgery for Intermediate Recurrent Risk of Papillary Thyroid Carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109769
Enrollment
Unknown
Registered
2025-09-24
Start date
2022-10-08
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Papillary Thyroid Carcinoma

Interventions

Helibacter Pylori Infection Group:None
Control Group (Non-infection):None

Sponsors

Guangzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with Papillary Thyroid Carcinoma Undergoing Initial Surgical Treatment; 2.Adult patients (age >=18 years old); 3.The patient or their legal guardian is able to understand the purpose of the study, is willing to comply with follow-up procedures, voluntarily agrees to participate, and signs a written informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with gastrointestinal disease, including: gastric cancer, inflammatory bowel disease (Crohn's disease, ulcerative colitis), and digestive tract malignancies, etc; 2. patients recently diagnosed with pancreatic diseases, including: acute and chronic pancreatitis, and pancreatic cancer; 3.patients who do not adhere to the prescribed L-T4 regimen; 4.patients who are taking calcium carbonate, sucralfate, or proton-pump inhibitors concurrently with L-T4 and cannot discontinue these medications.; 5.the recurrent cases of PTC; 6.pregnant woman; 7. Cases where TSH levels are within the standard range without the use of L-T4;

Design outcomes

Primary

MeasureTime frame
Thyroid Stimulating Hormone (TSH);

Countries

China

Contacts

Public ContactJianhua Feng

Guangzhou First People's Hospital

fengjianhua08@gmail.com+86 135 3397 4828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026