Non-small cell lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with advanced non-small cell lung cancer who visited our department in 2023 and were eligible for platinum-based chemotherapy regimens 2. Male or female patients aged 18 years or older 3. Treatment-naive patients with pathologically or cytologically confirmed NSCLC, stage IV disease 4. Patients expected to receive 3-4 cycles of chemotherapy 5. Patients with good compliance to treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with pathological type, staging, or survival status that do not meet the inclusion criteria 2. Patients with uncontrolled hypertension, unstable angina, history of myocardial infarction, or symptomatic congestive heart failure within 12 months prior to enrollment, or uncontrolled cardiac arrhythmias; electrocardiogram showing ischemic changes or clinically confirmed valvular heart disease 3. Patients with active bacterial, fungal, or viral infections 4. Pregnant or lactating patients 5. Patients with a history of other active malignancies besides NSCLC prior to enrollment 6. Patients with allergic diathesis or known or suspected hypersensitivity to any study medications 7. Patients with poor compliance 8. Patients deemed inappropriate for participation in this trial by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective Response Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival;Overall Survival;Proportion and Functional Status of B Cell Subsets; | — |
Countries
China
Contacts
The Fifth Affiliated Hospital of Guangzhou Medical University.