Stroke, with lower limb motor impairment
Conditions
Interventions
Level walking group:Level ground walk
Stair up and down group:Up and down stairs
Sponsors
Guabgzhou First People‘s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. be between 18 and 80 years of age at the time of consent; 2. meeting the diagnostic criteria of stroke related to Chinese Classification of Cerebrovascular Diseases 2015, confirmed by brain CT or MRI; 3. The muscle strength of the affected lower limb (MMT) was greater than grade ?; 4. able to perform transfer activities such as walking for more than 5 minutes; 5. stable cardiovascular disease (American Heart Association class B); 6. able to communicate with researchers, follow two-step instructions, and correctly answer informed consent understanding questions; 7. All subjects voluntarily cooperated with the study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with continuous deterioration or unstable vital signs; 2. having other serious medical conditions, such as being hospitalized due to a heart or lung disease within the past 3 months, such as having a pacemaker; 3. the presence of TMS contraindications, such as the presence of metallic foreign bodies, such as cochlear implants, internal pulse generators, aneurysm clips, intracranial stimulating electrodes, implantable defibrillators, etc. 4. severe ataxia or neglect (National Institutes of Health Stroke Scale item score >1), severe lower limb spasticity (Ashworth scale score >2/4, knee flexion, knee extension or ankle dorsiflexion); 5. recent history of illicit drug or alcohol abuse or severe mental illness; 6. The subjects had recently used the following drugs, such as sleeping pills, drugs that may reduce the seizure threshold, antidepressant drugs, etc. 7. The presence of lower extremity injury or disease such as grade ? meniscus injury and severe OA that limits lower extremity movement; 8. clinically significant neurological disorders other than stroke and other major medical conditions that may limit improvement or compromise safety; 9. Subjects or their family members did not cooperate, refused to sign the informed consent, or the investigator judged that it might be difficult for them to complete the study; 10. other conditions judged by the investigator to be ineligible for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of functional connectivity between motor and cognitive functional areas of the brain ?FC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of lower limb motor abilityAssessment of lower limb motor ability; | — |
Countries
China
Contacts
Public ContactYue Lan
Guabgzhou First People‘s Hospital
Outcome results
None listed