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Study on the Value of Pathogen Targeted Sequencing Technology in the Precise Application of Antibiotics for Patients with Lower Respiratory Tract Infections: A Prospective, Multicenter Cohort Study

Study on the Value of Pathogen Targeted Sequencing Technology in the Precise Application of Antibiotics for Patients with Lower Respiratory Tract Infections: A Prospective, Multicenter Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109756
Enrollment
Unknown
Registered
2025-09-24
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower respiratory infection

Interventions

Sponsors

The First Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Patients suspected of lower respiratory tract infection: 3. Use of antibiotics for more than 48 hours; 4. After assessment by a physician, conduct traditional microbiological testing or targeted pathogen sequencing of the respiratory tract.

Exclusion criteria

Exclusion criteria: 1. Incomplete clinical data; 2. Patients diagnosed with non-infectious diseases or chronic infections; 3. Patients with a history of allergic reactions to antibiotics or other severe allergic reactions; 4. Pregnant or breastfeeding women; 5. Individuals participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
The duration during which the patient received inappropriate antibacterial drug treatment;

Secondary

MeasureTime frame
Antibiotic treatment with drugs having antibacterial activity against Pseudomonas aeruginosa for one day;

Countries

China

Contacts

Public ContactYu Jing

The First Hospital of Hebei Medical University

yujing@hebmu.edu.cn+86 186 3388 5688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026