Scar
Conditions
Interventions
LCR Group:Laser type: CO2 LitescanF50
Parameter: 1008mj
Laser treatment: 1 laser in total
Radiotherapy: Radiotherapy is performed 24 hours after laser treatment and 7 days after treatment
Type of
Injection Group:Corticosteroid injection: Intralesional triamcinolone acetonide injection every 2 weeks
Treatment: Until keloid is smooth and soft, no more than 4 times.
Other treatment measures: N
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age = 16 years. 2. Diagnosed as keloid by at least 3 clinical physicians. 3. Keloid thickness >= 3 mm and <= 5 mm. 4. Fitzpatrick skin type III/IV.
Exclusion criteria
Exclusion criteria: 1. Keloids with active infection. 2. Men and women planning pregnancy in the near future, pregnant/postpartum women, or keloids located near the breast, thyroid, or gonads. 3. Severe dermatological conditions (e.g., psoriasis, scleroderma). 4. Hypoglycemia, anemia, or autoimmune diseases. 5. Clinically significant or unstable systemic diseases that may interfere with study safety outcomes, including malignancies, uncontrolled diabetes, uncontrolled hypertension, unstable pneumonia, organic kidney/liver diseases, unstable myocardial ischemia, dilated cardiomyopathy, conduction abnormalities, or unstable cardiovascular diseases. 6. Invasive treatments (e.g., corticosteroid injections, laser therapy) in the past year. 7. Patients with a history of radiotherapy at the lesion site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient and Observer Scar Assessment Scale, POSAS;Visual Analogue Scale, VAS;Image data; | — |
Countries
China
Contacts
Public ContactXiao-li Wu
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed