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Research on the Anatomical Mechanisms of Altered Functional Connectivity in Brain Lesions

Research on the Anatomical Mechanisms of Altered Functional Connectivity in Brain Lesions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109746
Enrollment
Unknown
Registered
2025-09-24
Start date
2022-11-05
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

BCI group:Conventional rehabilitation treatment+ BCI training

Sponsors

Shanxi Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) MRI or CT diagnosis of basal ganglia cerebral hemorrhage (involving the head of the caudate nucleus, the forelimbs and hind limbs of the internal capsule, the lentiform nucleus, or the external capsule area), accompanied by limb motor dysfunction; (2) First onset of the disease within 1-6 months; (3) Defined as age >=18, gender is not limited; (4) Simplified Mental State Score >=18, can understand and implement the training of the basic prompts and commands; (5) Patients who require rehabilitation treatment for functional area damage caused by functional impairment; (6) the subjects themselves or their legal representatives agreed to participate in the trial and signed a written informed consent form.

Exclusion criteria

Exclusion criteria: (1) the presence of serious cognitive, mental and psychological disorders; (2) serious heart, liver, kidney, lung and other important organ failure; (3) with upper limb defects, open wounds, deformities, or with severe pain; (4) suffering from severe vision, hearing impairment, claustrophobia, etc.; (5) the body contains metals that can not be cooperated with the magnetic resonance examination; (6) the subject is participating in other clinical trials at the same time.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer assessment,FMA;EEG;fMRI;

Secondary

MeasureTime frame
Mini-mental State Examination;The Modified Barthel Index;The brunnstrom staging;

Countries

China

Contacts

Public ContactJi Hongming

Shanxi Provincial People's Hospital

hongmingj@sina.com+86 137 5316 7077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026