myocardial injury of COVID-19
Conditions
Interventions
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ?Patients with initial diagnosis of COVID-19 infection? (Diagnostic criteria based on Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia [Trial Version 8] issued by the National Health Commission and State Administration of Traditional Chinese Medicine). 2. ?Patients exhibiting clinical symptoms of cardiac involvement? (e.g., chest tightness/pain) within 28 days of COVID-19 diagnosis, ?accompanied by? Electrocardiographic (ECG) abnormalities (e.g., ST-T segment changes) Elevated myocardial injury biomarkers (e.g., hs-cTnI), ?with no underlying diseases? (e.g., hypertension or diabetes). 3. ?Provision of informed consent? for study participation.
Exclusion criteria
Exclusion criteria: 1. ?Cardiogenic shock? 2. ?Prior myocardial infarction? 3. ?Cardiomyopathy? (dilated cardiomyopathy, hypertrophic cardiomyopathy, cardiomyopathy due to metabolic disorders, etc.), ?severe valvular heart disease, ?severe arrhythmias? 4. ?Severe renal insufficiency? (eGFR =30 ml/min/1.73m²) 5. ?Allergy to gadolinium-based contrast agents? 6. ?Contraindications to cardiac magnetic resonance imaging? (claustrophobia, allergy to gadolinium-based contrast agents, etc.) or ?presence of metallic implants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T1 value;T2 value;myocardial strain;radiomics feature; | — |
Countries
China
Contacts
Public ContactPan Jingwei
Shanghai Sixth People's Hospital
Outcome results
None listed