cancer pain
Conditions
Interventions
Test group:Dual catheter intrathecal drug infusion system implantation surgery
Control group:Single catheter intrathecal drug infusion system implantation surgery
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Those who do not respond to opioid treatment or are unable to tolerate toxic side effects; 2. VAS score >= 4 points, or breakthrough pain more than 3 times a day; 3. Expected survival period >= 3 months, heart function level I-II; 4. Pain occurs in both the neck and abdomen; 5. Patients and their families are informed of this study and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Severe drug dependence; 2. Severe blood diseases, aplastic anemia; 3. Severe systemic or local infection; 4. Skin problems and implant foreign body reactions and allergic reactions; 5. Psychiatric and psychological abnormalities; 6. History of drug or alcohol abuse; 7. Other contraindications for implantation, such as anatomical abnormalities, brain and spinal canal space occupying lesions; 8. Patients who refuse to sign informed consent forms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of pain relief;Adverse drug reactions;Quality of life score;Intrathecal drug dosage;Tolerance to analgesic drugs;painful outbursts;Opioid dosage(mg/d);Surgical adverse reactions;Supplementing oral morphine analgesic dosage; | — |
Countries
China
Contacts
Public ContactAimin Zhang
Sichuan Cancer Hospital
Outcome results
None listed