Delayed neurocognitive recovery
Conditions
Interventions
Sevoflurane anesthesia group (Group S):Sevoflurane
Ciprofol anesthesia group (Group C):Ciprofol
Sponsors
Baoding NO.1 central hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ASA Classification: Level II, III; 2. Patient age 60-80 years; 3. Patients undergoing elective laparoscopic colorectal tumor surgery under general anesthesia; 4. Voluntarily joining the study and signing the informed consent form; 5. Able to independently cooperate in completing the Montreal Cognitive Assessment (MoCA).
Exclusion criteria
Exclusion criteria: 1. Researchers who refuse to participate in this study; 2. Patients who are allergic to the anesthetics used in this study; 3. Those who cannot cooperate to complete the MoCA scale during the perioperative period; 4. Patients with severe cardiopulmonary disease and liver or kidney dysfunction; 5. Those whose preoperative MoCA scores do not meet the screening criteria (illiteracy <= 13 points, primary school <= 19 points, junior high school and above <= 24 points).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum inflammatory factors and oxidative stress indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age,Gender,ASA,BMI,Education level,Bleeding volume,Operative time; | — |
Countries
China
Contacts
Public ContactLi Xiaowei
Baoding No.1 Central Hospital
Outcome results
None listed