painless labor
Conditions
Interventions
control group:0.5 micrograms per milliliter of sufentanil + 0.1% ropivacaine, After administration of 12 ml of analgesic solution, connect the pulse pump in the epidural intermittent pulse mode, with
E1 group:0.25 mg/ml esketam + 0.1% ropivacaine, After administration of 12 ml of analgesic solution, connect the pulse pump in the epidural intermittent pulse mode, with a pulse dose of 6 ml/(time·h),
E2 group:0.5 mg/ml esketam + 0.1% ropivacaine, After administration of 12 ml of analgesic solution, connect the pulse pump in the epidural intermittent pulse mode, with a pulse dose of 6 ml/(time·h),
E3 group:0.75 mg/ml esketam + 0.1% ropivacaine, After administration of 12 ml of analgesic solution, connect the pulse pump in the epidural intermittent pulse mode, with a pulse dose of 6 ml/(time·h),
Sponsors
Chengde Central Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age range: 20 - 45 years old; single pregnancy, cephalic presentation, full-term pregnancy (= 37 weeks); agree to undergo epidural labor analgesia and sign the informed consent form; normal fetal heart rate, no signs of intrauterine distress; ASA classification: II - III; no other serious complications expected during the delivery process.
Exclusion criteria
Exclusion criteria: There are contraindications for epidural anesthesia, such as spinal deformity, infection, etc.; those who are known to be allergic to the components of the anesthetic drugs; those with severe diseases of the heart, lungs, liver, kidneys, etc.; those with pelvic abnormalities; and those who are expected to have serious complications during labor, such as severe preeclampsia, placental abruption, etc. Those with mental illnesses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edinburgh Postpartum Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesia-related indicators;blood sample;Anesthesia block situation; | — |
Countries
China
Contacts
Public ContactWang Wenxi
Chengde Central Hospital
Outcome results
None listed