chronically critical ill
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for severe sepsis patients: ICU days = 8 days and at least one of the following clinical characteristics, including: (1) PMV; (2) tracheotomy; (3) sepsis or other severe infections; (4) severe trauma; (5) multiple organ failure, cerebral ischemia, cerebral hemorrhage, or craniocerebral trauma. 2. Age >= 18 years old; 3. Cooperate with the follow-up personnel.
Exclusion criteria
Exclusion criteria: 1. Those with a history of diabetes or other endocrine diseases related to nutritional metabolism; 2. Patients with digestive system diseases and history of gastrointestinal surgery; 3. Patients with malignant tumors; 4. Those who have had severe organic lesions in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comprehensive Metabolic Panel;Circumference (waist circumference, hip circumference, abdominal circumference, middle arm circumference, calf circumference, skinfold thickness);Chest/Abdominal Computed Tomography;Nutrition risk screening;Nutrition Risk in the Critically Ill Score;Mini nutritional assessment;Barthel Index;The MOS item short from health survey;Eating assessment tool;Acute gastrointestinal injury;Echocardiogram;Brain natriuretic peptide;Diamine Oxidase;Index of intestinal mucosal barrier damage;Intestinal type analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;Weight;Murray Lung Injury Score;Electrocardiogram;cardiopulmonary exercise testing;Rate of Perceived Exertion;International Physical Activity Questionnaire;Mini-mental State Examination;Glasgow Coma Scale;Self-Rating Anxiety Scale ;Patien Health Questionnare-9;Pittsburgh Sleep Quality Index ;Padua Prediction Score; | — |
Countries
China
Contacts
Beijing Rehabilitation Hospital of Capital Medical University