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Comparative Study on Clinical Effects of Oxycodone and Sufentanil in Labor Analgesia for Parturients

Comparative Study on Clinical Effects of Oxycodone and Sufentanil in Labor Analgesia for Parturients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109665
Enrollment
Unknown
Registered
2025-09-23
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epidural labor analgesia

Interventions

Sufentanil group:Administering epidural labor analgesia with sufentanil
Oxycodone group:Administering epidural labor analgesia with oxycodone

Sponsors

Ningbo Beilun People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Nulliparas aged 18-35 years, with cephalic presentation and singleton pregnancy, and gestational age of 37-42 weeks at delivery; 2. Eligible for vaginal trial labor, without underlying diseases such as cardiopulmonary diseases, and with American Society of Anesthesiologists (ASA) physical status ?-?; 3. Cervical dilation of 2-3 cm; 4. No allergy to sedative drugs; 5. All patients are informed of the study and voluntarily participate in it;

Exclusion criteria

Exclusion criteria: 1. Having contraindications to epidural anesthesia (such as coagulation dysfunction, spinal deformity, local infection, etc.); 2. Long-term use of sedative or analgesic drugs; 3. Complicated with severe cardiopulmonary diseases, autoimmune diseases, HELLP syndrome or other underlying diseases that may affect the study results; 4. Any conditions that lead to inability to cooperate with the study, such as mental illness, etc. 5. Those undergoing induction of labor.

Design outcomes

Primary

MeasureTime frame
Compare the incidence of adverse reactions after anesthesia administration between the two groups;Analgesic effect and PCEA drug dosage;Visual Analogue Scale (VAS);

Secondary

MeasureTime frame
duration of labor;delivery mode;Neonatal Apgar score;

Countries

China

Contacts

Public ContactXu Rong

Ningbo Beilun People’s Hospital

516069717@qq.com+86 574 8610 4293

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026