Early gastric cancer
Conditions
Interventions
Gold Standard:Gastroscopy + pathology
Index test:Plasma biomarker early gastric cancer diagnosis model
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Stomach cancer group: 1. Gastroscopy at the Endoscopy Center of Peking University First Hospital; 2. Complete clinical data; 3. Signed informed consent; 4. Age >= 18 and = 18 and <= 80 years; 5. No known malignant tumors outside of the stomach.
Exclusion criteria
Exclusion criteria: Gastric cancer group: 1. Age 80 years; 2. Known concurrent or past malignant tumors at other sites besides gastric cancer; 3. Underwent treatments such as endoscopy, surgery, or chemotherapy/radiotherapy; 4. Refusal to participate in the study or incomplete clinical data; 5. Concurrent metabolic diseases or hematologic disorders; 6. Concurrent underlying diseases such as cardiovascular, liver, or kidney diseases; 7. Women in lactation or pregnancy; 8. Significant stress response occurred within 2 weeks before blood sampling; 9. Any acute disease symptoms within 2 weeks before blood sampling; 10. Special medications (antibiotics, hormones, non-steroidal anti-inflammatory drugs, etc.) taken within 2 weeks before blood sampling. Healthy control group: 1. Age 80 years; 2. Known concurrent or past malignant tumors at other sites besides gastric cancer; 3. Underwent treatments such as endoscopy, surgery, or chemotherapy/radiotherapy; 4. Refusal to participate in the study or incomplete clinical data; 5. Concurrent metabolic diseases or hematologic disorders; 6. Concurrent underlying diseases such as cardiovascular, liver, or kidney diseases; 7. Women in lactation or pregnancy; 8. Significant stress response occurred within 2 weeks before blood sampling; 9; Any acute disease symptoms within 2 weeks before blood sampling; 10. Special medications (antibiotics, hormones, non-steroidal anti-inflammatory drugs, etc.) taken within 2 weeks before blood sampling.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| General data;Information on endoscopy;Pathological findings;Performance evaluation indicators of diagnostic models; | — |
Countries
China
Contacts
Public ContactFeng Wang
Peking University First Hospital
Outcome results
None listed