Repair and correction of dental defects and missing teeth
Conditions
Interventions
Experimental group:During the second stage, the H-PRF membrane is simultaneously used for soft tissue thickening
Control group:During the second-stage surgery, de-epithelialized gingival tissue is simultaneously used for soft tissue thickening
Sponsors
Stomatological Hospital of Wuhan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with missing maxillary anterior teeth (at most two teeth) who have placed dental implant at least 3 months. 2. The tissue contour at the implant site exhibits collapse compared to the adjacent natural teeth before stage-two surgery. 3. The mesial and distal adjacent teeth present with good periodontal status. 4. The palatal mucosa in the donor site exhibited normal morphology. 5. The patient had no uncontrolled systemic diseases. 6. Patients with good oral environment and high compliance. 7. The patients voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women and individuals with pregnancy plans within the next 6 months. 2. Heavy smokers (>10 cigarettes/day). 3. Patients with severe diseases of vital organs (heart, liver, lung, kidney) or uncontrolled serious hematologic, immune, or endocrine disorders, as well as any metabolic disease that may negatively affect soft tissue healing. 4. Poorly controlled diabetes (fasting blood glucose =8.0 mmol/L despite medication). 5. Patients with untreated periodontitis, acute apical periodontitis, periapical abscess, and/or moderate to advanced periodontal disease. 6. Patients with poor oral hygiene who cannot maintain adequate oral care. 7. Patients taking medications that cause gingival enlargement or the presence of gingival idiopathic overgrowth. 8. Perioperative use of medications that may interfere with tissue repair, including but not limited to glucocorticoids and other anti-inflammatory agents. 9. Soft tissue augmentation has been done in the implant site.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soft tissue thickness at the labial alveolar ridge crest level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Soft tissue thickness change at 1mm and 2mm level below the labial alveolar ridge crest;Surgical time;Peri-implant tissue health status (including plaque index, bleeding on probing, probing pocket depth , and marginal bone level);Marginal bone loss;Aesthetic evaluation;Patient satisfaction and comfort;Soft tissue volume change; | — |
Countries
China
Contacts
Public ContactZhang Yufeng
Stomatological Hospital of Wuhan University
Outcome results
None listed