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Study on the Dosage of Propofol for Suppressing Responses to Endotracheal Intubation under General Anesthesia in High-Altitude Areas

Study on the Dosage of Propofol for Suppressing Responses to Endotracheal Intubation under General Anesthesia in High-Altitude Areas

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109641
Enrollment
Unknown
Registered
2025-09-23
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgical patient

Interventions

Propofol Sequential Test Group:1. The intervention in this study is the dosage regimen of intravenous Propofol Emulsion Injection (manufacturer: Xi'an Libang Pharmaceutical Co., Ltd.). All doses are a

Sponsors

People's Hospital of Changdu City, Xizang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients scheduled for endotracheal intubation under general anesthesia, regardless of gender, aged 18 to 65 years, with BMI between 18 and 28 kg/m², ASA (American Society of Anesthesiologists) Class I or II, Mallampati Class I or II, normal mouth opening, and normal head and neck movement.

Exclusion criteria

Exclusion criteria: Difficult airway or potentially difficult airway, uncontrolled or poorly controlled systemic diseases (such as hypertension, diabetes), pregnancy, alcoholism, allergy to study drugs, history of illegal drug use, neurological diseases, or inability to communicate effectively. In addition, initial tracheal intubation failure, occurrence of emergencies during induction, and use of vasoactive drugs

Design outcomes

Primary

MeasureTime frame
MOAA/S Assessment Scale;blood pressure;heart rate;

Countries

China

Contacts

Public ContactLi Shuiying

People's Hospital of Changdu City, Tibet

15123229435@163.com+86 151 2322 9435

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026