Mycophenolate mofetil is used for maintenance immunosuppressive therapy after kidney transplantation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. First-time kidney transplant recipients, at least 3 months since the kidney transplant; 3. Usage of imatinib for at least 1 month; 4. Long-term regular follow-up at Sichuan University West China Hospital outpatient clinic.
Exclusion criteria
Exclusion criteria: 1. White blood cell count 3 times normal upper limit or total bilirubin > 2 times normal upper limit); 10. Presence of any comorbidity that is expected to reduce life expectancy to less than 2 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concentration of imidazole;The concentration of tacrmos;Creatinine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Red blood cells under uroscopy;Photosuppressin C;BK viral load (urine);Haemoglobin;Cholesterol;Adverse event;Triglyceride;BK virus load (blood);Lymphocyte ratio (blood routine);Urine protein;UA (uric acid);Serum urea nitrogen;Creatinine clearance rate;White blood cell;Platelets; | — |
Countries
China
Contacts
Department of Nephrology, West China Hospital, Sichuan University