Children with Rolandic Epilepsy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Epilepsy group: Children aged 6 to 14 years diagnosed with Rolandic epilepsy according to the 2017 ILAE classification of seizures and epileptic syndromes. Control group: 1. No history of neurological or psychiatric disorders; 2. Normal findings on routine cranial MRI; 3. Matched for gender, age, and level of education with the epilepsy group; 4. No contraindications to MRI scanning; 5. Written informed consent obtained from guardians, and participants are cooperative during examinations.
Exclusion criteria
Exclusion criteria: Epilepsy group: 1. Coexisting neurological or psychiatric disorders; 2. History of long-term corticosteroid use; 3. MRI artifacts; 4. Head motion with translation exceeding 3 mm or rotation exceeding 3°; 5. Organic lesions identified on cranial MRI. Control group: 1. Children clinically diagnosed with precocious puberty, idiopathic short stature, or those receiving hormone therapy; 2. Head motion with translation exceeding 3 mm or rotation exceeding 3°; 3. MRI artifacts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Structural network node attributes;Structural network global properties;Pediatric clinical information (age, gender, mode of delivery, birth weight, perinatal complications, age of seizure onset, disease duration, frequency of seizures, treatment status);Parental information (parental age, number of pregnancies, number of births, educational level, family history of epilepsy, clinical neuropsychological assessment, etc.); | — |
Countries
China
Contacts
Chengdu Women`s and Children`s Central Hospital, School of Medicine,University of Electronic Science and Technology of China