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Effect of esketamine preemptive analgesia on recovery and pain after laparoscopic cholecystectomy

Effect of esketamine preemptive analgesia on recovery and pain after laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109577
Enrollment
Unknown
Registered
2025-09-22
Start date
2023-02-23
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis

Interventions

Observation group:Intravenous injection of 0.25mg/kg esketamine 30min before peeling
Control group:Intravenous injection of 0.9%NS 30min before peeling

Sponsors

The Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People’s Hospital of Shenzhen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18~65 years old; 2. ASA grade 1~2; 3. Laparoscopic cholecystectomy in general surgery.

Exclusion criteria

Exclusion criteria: 1. History of hypertension, coronary heart disease, or abnormal cardiopulmonary function, severe liver and kidney function; 2. Recent history of analgesic and sedative drugs, and history of narcotic analgesic drug addiction or drug use.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale;

Secondary

MeasureTime frame
Ramsay Sedation Scale;Ramsay Sedation Scale;Tracheal catheter removal time;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactZhu Qiuyu

The Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People’s Hospital of Shenzhen

1797362059@qq.com+86 136 8236 2302

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026