Retinopathy of Prematuity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Infants weighing less than 1500g diagnosed with Type I Retinopathy of Prematurity (ROP) by two experienced ophthalmologists require anti-VEGF treatment. This includes cases such as Zone I Stage 1+, Zone I Stage 2+, Zone I Stage 3+, Zone I Stage 3, Zone II Stage 2+, Zone II Stage 3+, and aggressive posterior ROP ; 2. Family members of the infants must be willing to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Infectious diseases such as HIV, syphilis, hepatitis, or cytomegalovirus infection. 2. Major systemic diseases, such as congenital metabolic disorders or hematologic diseases. 3. Other ocular abnormalities, including congenital cataracts, glaucoma, or defects. 4. Major systemic malformations. 5. Coagulation disorders or medications that may affect metabolic status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma metabolities;Cure rate of retinopathy of prematurity; | — |
Countries
China
Contacts
The Second Affliated Hospital of Harbin Medical University