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Effect of growth hormone on embryo outcomes of infertile patients with available embryos rate<=1/3: A single-arm, self-controlled before-and-after clinical study

Effect of growth hormone on embryo outcomes of infertile patients with available embryos rate<=1/3: A single-arm, self-controlled before-and-after clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109561
Enrollment
Unknown
Registered
2025-09-22
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility, low rate of available embryos

Interventions

Experimental group:Subcutaneously injection of growth hormone

Sponsors

The First People's Hospital of Foshan
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 42 Years

Inclusion criteria

Inclusion criteria: 1. Women who underwent in vitro fertilization and embryo transfer (IVF/ICSI) treatment due to infertility in the Reproductive Medical Center of the First People's Hospital of Foshan, 20 years old <= age <=42 years old; 2.At least one cycle of IVF/ICSI treatment without the use of growth hormone (GH) in the previous treatment, the available embryo rate <=1/3 (including the patient with zero retrieved oocytes), and the number of available embryos <=3; 3. Need to continue the second cycle of IVF/ICSI treatment; 4. Signed the informed consent, promised to abide by the research procedures, and cooperated with the implementation of the whole process of the study.

Exclusion criteria

Exclusion criteria: 1.There were uterine malformations, intrauterine adhesions; 2.The presence of chromosomal abnormalities in either spouse; 3.There are contraindications to the use of GH: history of malignant tumors, history of immunosuppressive treatment due to severe rheumatic immune diseases, severe infections, diabetes, hypothyroidism, and hemangiomas.

Design outcomes

Primary

MeasureTime frame
Available embryo rate, available embryo number;

Secondary

MeasureTime frame
Number of oocytes, number of good quality embryos, good quality embryo rate, number of blastocyst formation, blastocyst formation rate;Fresh embryo transfer cancellation rate, fresh embryo transfer HCG positive rate, fresh embryo transfer clinical pregnancy rate, fresh embryo transfer early abortion rate;

Countries

China

Contacts

Public ContactWang Meng

The First People's Hospital of Foshan

1042223855@qq.com+86 757 8316 2414

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026