Mild cognitive impairment
Conditions
Interventions
Group 1:CCT Training, 30 minutes per session, 3 times a week, for a total of 12 weeks
Group 2:CCT Training, 45 minutes per session, 3 times a week, for a total of 12 weeks
Group 3:CCT Training, 60 minutes per session, 3 times a week, for a total of 12 weeks
Group 4:CCT Training, 30 minutes per session, 5 times a week, for a total of 12 weeks
Group 5:CCT Training, 45 minutes per session, 5 times a week, for a total of 12 weeks
Group 6:CCT Training, 60 minutes per session, 5 times a week, for a total of 12 weeks
Sponsors
Peking University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=60 years old; 2. Self-reported cognitive decline, and confirmed by an insider; 3. Score of 19 to 25 on the Montreal Cognitive Assessment (MoCA) scale (adjusted according to the years of education: 1 point for those with 6 years or less of education); 4. Maintain the ability to independently complete daily activities; 5. Possess basic communication skills and be able to cooperate in completing research. 6. Voluntarily participate in the research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from underlying neurological diseases that may impair cognitive function, including but not limited to dementia syndrome, Parkinson's disease, epilepsy, cerebrovascular diseases, etc. 2. Suffering from severe or unstable organic diseases such as cancer, hydrocephalus, central nervous system tumors, or acute brain injury/infection; 3. Suffering from severe mental illnesses such as major depression, schizophrenia, schizoaffective disorder, bipolar disorder, etc. 4. There are severe visual or hearing impairments, or other physical conditions that may hinder the completion of the research; 5. Those who have participated in any other clinical trials within the past three months; 6. Have received transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), phototherapy for any reason within the past six months, or have taken drugs that may significantly affect cognitive function (such as psychotropic drugs, psychoactive drugs, anticholinergic drugs, benzodiazepines, etc.); 7. There is a history of alcohol dependence or substance abuse; 8. Drinking alcohol or using other substances that affect cognitive function, such as coffee or cocaine, within 24 hours before the cognitive assessment; 9. The researcher believes that there are circumstances that are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mental health status at weeks 4, 12, and 24 post-randomization.;Cognitive performance in sub-domains at weeks 4, 12, and 24 post-randomization.;Functional activities at weeks 4, 12, and 24 post-randomization.;Change from baseline in MoCA scale scores at weeks 4 and 24 post-randomization.; | — |
Countries
China
Contacts
Public ContactHaibo Wang
Peking University
Outcome results
None listed