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A Clinical Study on the Improvement of Cognitive Function in Patients with Schizophrenia Using Transcranial Temporal Interference Stimulation Technology

A Clinical Study on the Improvement of Cognitive Function in Patients with Schizophrenia Using Transcranial Temporal Interference Stimulation Technology

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109557
Enrollment
Unknown
Registered
2025-09-22
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia with Cognitive Impairment

Interventions

Active tTIS:Active tTIS
Sham tTIS:Sham tTIS

Sponsors

Affiliated Kangning Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meeting the Diagnostic Criteria for Schizophrenia According to the DSM-5; 2.Aged 18 to 65 years; 3.Right-handed; 4.Having signed informed consent;

Exclusion criteria

Exclusion criteria: 1.With severe agitation, impulsivity, or tendencies of self-harm or suicide; 2.With contraindications to treatment, such as intracranial metallic implants; 3.Having received electroconvulsive therapy or other physical treatments within the past month; 4.Pregnancy; 5.History of alcohol or other psychoactive substance abuse; 6.With severe physical illness;

Design outcomes

Primary

MeasureTime frame
MCCB score;

Secondary

MeasureTime frame
Neurophysiological indicators drived from eletropgysiology and neuroimaging;Scores of other clinical symptoms and social function-related scales;Neurobiochemical indices;Cognitive-behavioral task indices, such as accuracy and reaction time;Scores of the Adverse Event Record Form;

Countries

China

Contacts

Public ContactDongsheng Zhou

Affiliated Kangning Hospital of Ningbo University

wyzhouds@sina.com+86 574 2630 2565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026