Heart valve disease/ Coronary disease
Conditions
Interventions
Control group:Eating between 20:00 and 22:00 on the day before the operation, and fasting after 22:00
Experimental group:Eating between 12:00 and 14:00 on the day before the operation, and fasting after 14:00
Sponsors
Department of Anesthesiology, First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years and above undergoing heart surgery primarily involving valve replacement/repair and/or coronary artery bypass under extracorporeal circulation at a scheduled time in the morning; 2. Patients who can eat normally by mouth; 3. ASA classification II to III; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery, deep hypothermic cardiopulmonary bypass surgery; 2. Time-limited fasting, use of medications such as Metformin and Semaglutide for weight loss; 3. Low body weight (BMI = 37.5 kg/m^2); 4. Acute infections treated with antibiotics; 5. Endocarditis, EF 21 umol/L (sub-center > upper limit of detection) or INR > 2.0]; 10. Heparin-induced type II thrombocytopenia; 11. Unable to communicate or enroll in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of major complications after surgery in hospital; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of major complications and the incidence of single complications within 30 days after the surgery;The incidence of major complications and the incidence of single complications within 90 days after the surgery;time of mechanical ventilation, ICU stay and hospital stay;Incidence of new postoperative onset atrial fibrillation;Incidence of postoperative delirium;Incidence of postoperative infection rate;Perioperative vasoactivity-inotropic drug score;Laboratory indicators; | — |
Countries
China
Contacts
Public ContactJiaolin Ning
Department of Anesthesiology, First Affiliated Hospital of Army Medical University
Outcome results
None listed