Lung surgery
Conditions
Interventions
enrikefon group:Patients received 1ug/kg enrikefon in 20mL 0.9% normal saline infusion 30min before the start of surgery. The PCIA pump was connected at the end of the operation, and the formula was s
control group:20mL of 0.9% saline was injected intravenously 30min before the start of the procedure. At the end of operation, PCIA pump was connected with the formula of sufentanil 3 µg/kg and flurb
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who intend to electively undergo thoracoscopic partial lung resection under general anesthesia; 2. Age 18-65 years, gender is not limited; 3. American Society of Anesthesiologists (ASA) grade I-III; 4. Know, agree to participate in the trial and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1.patients with a history of allergy to opioids or local anesthetics, or allergy to intraoperative anesthetics specified in the protocol; 2.patients with preoperative chronic pain or long-term use of analgesics; 3.severe heart disease (NYHA class III or IV), liver disease (Child-Pugh score 10-15), kidney disease (renal replacement therapy), hematopoietic system disease (leukemia); 4.patients with preoperative mental disease, language disorder, or other factors leading to communication difficulties and unable to complete the scale assessment; 5.refused to participate or participated in other clinical research in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative fatigue syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative quality of recovery;Pain score;Opioid-related adverse reactions;Postoperative opioid use;Postoperative sleep quality; | — |
Countries
China
Contacts
Public ContactChen Lijian
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed