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Comparison of the genicular nerve block and the iPACK (Interspace Between the Popliteal Artery and Capsule of the Posterior Knee) used in Combination With the Adductor Canal Block in total knee arthroplasty:A prospective randomized controlled trial.

Comparison of the genicular nerve block and the iPACK (Interspace Between the Popliteal Artery and Capsule of the Posterior Knee) used in Combination With the Adductor Canal Block in total knee arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109484
Enrollment
Unknown
Registered
2025-09-19
Start date
2025-09-19
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesi of total knee arthroplasty

Interventions

GNB Group:Adductor canal block combined with GNB block before operation.
IPACK Group:Adductor canal block combined with IPACK block before operation.
Control group:Adductor canal block before operation.

Sponsors

The Third People's Hospital of Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adult patients aged 18 to 80, classified by American College of Anesthesiologists as I to III, plan to undergo elective unilateral total knee arthroplasty under general anesthesia.

Exclusion criteria

Exclusion criteria: Contraindication to a nerve block, other connective tissue diseases affecting the knee, allergy to local anesthesia, sciatic pain, hepatic and renal insufficiency,body mass index (BMI) higher than 40 kg/m^2, use of anticoagulant drugs, age 80 years, inability to comprehend or cooperate to perform this study and refusal of regional block .

Design outcomes

Primary

MeasureTime frame
The NRS pain score during movement;

Secondary

MeasureTime frame
The NRS pain score during rest;Systolic pressure;Diastolic pressure;Heart rate;Recovery time of postoperative spontaneous respiration;Waking time;PACU stay time;Sufentanil consumption;AUC for pain score during the first 12 h;AUC for pain score during the first 24 h;McMaster Universities Arthritis Index (WOMAC);Oxford Knee Score (OKS);Knee Society Score (KSS);Medical Research Council (MRC) scale;Range of Motion(ROM) Test;Timed Up and Go (TUG) test;

Countries

China

Contacts

Public ContactHao Jin

The Third People's Hospital of Chengdu

sgzzxh2008@126.com+86 28 6131 8776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026