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Comparison of the clinical efficacy and safety of endoscopic superior rectal mucosal ligation and hemorrhoids ligation

Comparison of the efficacy and safety of endoscopic superior rectal mucosal ligation and hemorrhoids ligation: a single-center randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109474
Enrollment
Unknown
Registered
2025-09-18
Start date
2024-07-19
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhoids

Interventions

Endoscopic superior rectal mucosal ligation group:The patient takes the left side decubitus position, the endoscope is connected with 6 serial ligators, the cup of the sleeve is pointed at the upper e
Endoscopic hemorrhoid ligation group:The patient takes the left side decubitus position,the endoscope is connected with 6 serial ligators,the cup the sleeve is aligned with the base of the hemorrhoid

Sponsors

The Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. According to the Goligher classification in the Chinese guidelines for the diagnosis and treatment of hemorrhoids (2020) , patients who are diagnosed with grade II-III internal hemorrhoids . 2. Patients who voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who had severe heart, liver, and kidney disease. 2. Patients who had severe immune deficiency. 3. Patient's general condition was too poor to tolerate endoscopic therapy. 4. Patientshad a history of pelvic chemoradiotherapy. 5. Patients had severe infection or inflammatory lesion in the rectum or anal canal,or the rectum or anal canal had undergone surgery. 6. Patient is a pregnant woman. 7. Patients who disagreed with endoscopic treatment and were concerned about the possible risks refused to sign the informed consent form. 8. The follow-up time was insufficient and the clinical data were incomplete.

Design outcomes

Primary

MeasureTime frame
Clinical efficacy;

Secondary

MeasureTime frame
Recurrence rate;Improvement degree of hemorrhoid-related scores;Adverse event rate;

Countries

China

Contacts

Public ContactQi Xingsi

The Affiliated Hospital of Qingdao University

qixingsi@163.com+86 186 6180 9467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026