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Building a Risk Prediction Model for the Onset of Generalized Pustular Psoriasis Based on Relevant Clinical Characteristics

Building a Risk Prediction Model for the Onset of Generalized Pustular Psoriasis Based on Relevant Clinical Characteristics

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109469
Enrollment
Unknown
Registered
2025-09-18
Start date
2025-09-20
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Generalized pustular psoriasis, GPP

Interventions

Group of generalized pustular psoriasis:None
Group of psoriasis vulgaris:None

Sponsors

Chengdu Rheumatism Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meets the relevant diagnostic criteria for GPP and PV; 2. Aged between 18 and 80 years; 3. Signed informed consent; 4. Normal cognitive function and able to cooperate in completing the clinical assessments and follow-ups required for this study; 5. Complete clinical data and able to provide detailed medical history, treatment history, and imaging examination results.

Exclusion criteria

Exclusion criteria: 1. Patients with atopic dermatitis, contact dermatitis, and other skin diseases; 2. Those who have received systemic immunosuppressive therapy or systemic corticosteroid therapy within the 6 months prior to enrollment; 3. Patients with abnormal cardiac, liver, or kidney function; 4. Patients with concurrent tuberculosis infection, respiratory infections, or other acute or chronic infections; 5. Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Highly sensitive C-reactive protein, white blood cell count, erythrocyte sedimentation rate, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol;

Secondary

MeasureTime frame
A. Body Mass Index; B. Age; C. Gender; D. Length of hospital stay; E. Smoking history; F. Drinking history; G. Family history; H. Anemia history; I. Hyperlipidemia history; J. Skin secondary infection history;

Countries

China

Contacts

Public ContactNie Xinning

Chengdu Rheumatism Hospital

2585164839@qq.com+86 28 8611 7707

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026