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Comparison of clinical outcomes between enhanced recovery after surgery and traditional perioperative management in laparoscopic hepatectomy

Comparison of clinical outcomes between enhanced recovery after surgery and traditional perioperative management in laparoscopic hepatectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109462
Enrollment
Unknown
Registered
2025-09-18
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cancer,Intrahepatic lithiasis.

Interventions

Control group:Traditional perioperative management group
ERAS Group:ERAS protocol for hepatobiliary surgery

Sponsors

Guizhou Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Preoperatively diagnosed clearly and eligible for elective laparoscopic liver resection under general anesthesia. 2. Good liver function: Child-Pugh grade A or B (partially), and ALT/AST = 18.5, albumin >= 30g/L), and preoperative prognostic nutritional index (PNI) < 50%. 5. Normal gastrointestinal function preoperatively and stable vital signs postoperatively. 6. Age 18-75 years, gender unrestricted. 7. Understanding the content of the informed consent form, voluntarily participating in this study, signing the informed consent form, and able to cooperate with postoperative follow-up.

Exclusion criteria

Exclusion criteria: 1. Refusal to participate in this study; 2. Pregnant or lactating women; 3. Patients undergoing emergency surgery or combined with other organ removal surgeries; 4. More than 1000ml of blood loss during the operation; 5. Conversion to open surgery during the operation; 6. Transfer to the intensive care unit after the operation; 7. Previous history of complex upper abdominal surgeries. 8. Previous history of anaphylaxis to local anesthetics or other anesthetic drugs; 9. Compromised coagulation function, heart failure, respiratory failure, uncontrolled hypertension, diabetes, history of peptic ulcer or gastrointestinal bleeding, renal dysfunction or immunosuppressive agent status; 10. Patients with chronic pain and mental disorders, those who have been using sedatives and analgesics for a long time before the surgery, or those who have used antipsychotic drugs recently, alcoholics or drug abusers; 11. Unable to provide written materials; 11. Unable to understand written or spoken language, patients who were unable to communicate due to coma, severe dementia or language disorders before the operation.

Design outcomes

Primary

MeasureTime frame
The NRS scale after surgery;

Secondary

MeasureTime frame
Postoperative intestinal function recovery time;The usage of opioid drugs 72 hours after surgery;

Countries

China

Contacts

Public ContactKaiyun Fang

Guizhou Provincial People's Hospital

fangkaiyun@sina.cn+86 139 8553 3277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026