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Understanding Bladder Neck Narrowing After Different Types of Prostate Surgery

Mechanisms and Risk Factors of Bladder Neck Contracture After Different Surgical Treatments for Benign Prostatic Hyperplasia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109420
Enrollment
Unknown
Registered
2025-09-18
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Neck Contracture

Interventions

Transurethral Resection of the Prostate Group:None
Photoselective Vaporization of the Prostate Group:None
Holmium Laser Enucleation of the Prostate Group:None

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years old, male; 2.Patients are clinically diagnosed with benign prostatic hyperplasia (BPH) in accordance with the diagnostic criteria established by the Chinese Urological Association BPH Guidelines. The main criteria are as follows: Lower urinary tract symptoms (LUTS) consistent with typical BPH presentation, such as weak urinary stream, nocturia, urinary frequency, and urgency; Imaging findings (ultrasound or MRI) indicating prostate enlargement; PSA test not suggesting a high risk of malignancy, or prostate cancer has been ruled out; 3.Preoperative imaging evaluation (e.g., transabdominal or transrectal ultrasound, elastography) has been performed with clear image quality; 4.Agree to collect preoperative blood and urine samples for subsequent molecular marker research; 5.Planned to receive surgical intervention treatments (such as TURP, green laser PVP, HoLEP, water jet vaporization, etc.); 6.It has complete preoperative clinical assessment data, including IPSS, Qmax, residual urine volume and prostate "Product, PSA, etc."; 7.Have the ability to sign informed consent and voluntarily participate in this research.

Exclusion criteria

Exclusion criteria: 1.Patients with confirmed or suspected prostate cancer (e.g., biopsy indicating adenocarcinoma or elevated PSA without definitive exclusion of malignancy); 2.Patients with a history of prior prostate-related surgical treatments (e.g., TURP, PVP, HoLEP, etc.); 3.Patients with severe organ dysfunction (e.g., liver or renal failure), active infections, immune system disorders, or psychiatric illnesses; 4.Patients who are unable to provide essential preoperative or intraoperative data (e.g., imaging records, surgical parameters) or tissue samples; 5.Patients who refuse to participate or are unable to comply with study procedures and follow-up.

Design outcomes

Primary

MeasureTime frame
International Prostate Symptom Score;Post-Void Residual Volume;Maximum Urinary Flow Rate;

Secondary

MeasureTime frame
Prostate Volume;Perioperative Complications;

Countries

China

Contacts

Public ContactQi Zhang

Zhejiang Provincial People's Hospital

clinic@126.com+86 13858019285

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026