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Study on the effect of hyperbaric oxygen combined with gingival repair membrane on the preservation of tooth extraction sites in patients with periodontitis

Study on the effect of hyperbaric oxygen combined with gingival repair membrane on the preservation of tooth extraction sites in patients with periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109400
Enrollment
Unknown
Registered
2025-09-17
Start date
2025-10-15
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with periodontitis have bad teeth that need to be extracted

Interventions

ARP+HOT:Alveolar ridge preservation using gingival repair membranes,Hyperbaric oxygen therapy for postoperative care.
ARP:Alveolar ridge preservation using gingival repair membranes

Sponsors

Beijing Haidian Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Mandibular molars that cannot be preserved; 2.Severe alveolar bone resorption but at least two bone walls with a remaining height of >= 3 mm; 3.At least one adjacent tooth exists; 4.According to the 2018 periodontitis classification system, oral periodontal disease is diagnosed as grade III or IV; 5.The subjects signed a complete informed consent.

Exclusion criteria

Exclusion criteria: 1.Smoking > 10 cigarettes/day; 2.Pregnant or breastfeeding women; 3.History of head and neck radiation therapy; 4.Long-term use of drugs that affect bone metabolism or bone healing; 5.Presence of systemic diseases such as hypertension and diabetes; 6.Patients with severe neurological or respiratory diseases who are assessed by the study physician as unsuitable for hyperbaric oxygen therapy; 7.Significantly crowded or twisted teeth; 8.The tooth has an acute infection (abscess or pus discharge).

Design outcomes

Primary

MeasureTime frame
Bone tissue volume;

Secondary

MeasureTime frame
Soft tissue volume;Salivary proteins;PROMs;

Countries

China

Contacts

Public ContactRuiyong Wang

Beijing Haidian Hospital

wangruiyong@163.com+86 10 82693113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026