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Comparison of Analgesic Efficacy and Recovery Quality Between Epidural Block Combined with General Anesthesia versus Combined Transversus Abdominis Plane Block and Rectus Sheath Block with General Anesthesia in Single-Incision Laparoscopic Cholecystectomy

Comparison of Analgesic Efficacy and Recovery Quality Between Epidural Block Combined with General Anesthesia versus Combined Transversus Abdominis Plane Block and Rectus Sheath Block with General Anesthesia in Single-Incision Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109393
Enrollment
Unknown
Registered
2025-09-17
Start date
2025-09-23
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallbladder stones or gallbladder polyps

Interventions

Epidural anesthesia combined with general anesthesia group:Before anesthesia induction, the patient was positioned on their left side, and an epidural puncture was performed at the T9-10 level. After
Nerve block combined with general anesthesia group:After the successful intubation during anesthesia induction, a fascia plane block was performed under ultrasound guidance. After disinfection and dra

Sponsors

Zhongshan Hospital , Fudan University (Xiamen Branch)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective single-incision laparoscopic cholecystectomy; 2. American Society of Anesthesiologists (ASA) Physical Status Classification of I-II; 3. Age between 18 and 65 years, regardless of gender; 4. The patient or their legally authorized representative has provided informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to epidural blockade or nerve blockade; 2. Comorbidities including choledocholithiasis, gallbladder malignancy, or cirrhotic portal hypertension; 3. Coagulation disorders or current use of anticoagulant medications; 4. History of psychiatric disorders or cognitive impairment; 5. Pre-existing chronic pain or long-term use of analgesic medications; 6. Inability to cooperate with postoperative pain assessment or follow-up; 7. Failure to provide written informed consent.

Design outcomes

Primary

MeasureTime frame
the 24-h postoperative Quality of Recovery-15 (QoR-15) score;

Secondary

MeasureTime frame
the 48-h postoperative Quality of Recovery-15 (QoR-15) score;Pain rating at rest and during exercise;Opioid consumption;Postoperative functional recovery indicators;The incidence and severity of postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactWu Junmei

Zhongshan Hospital , Fudan University (Xiamen Branch)

wu.junmei@zsxmhospital.com+86 158 8043 6535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026