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Effects of different modes of transcranial direct current stimulation on rehabilitation and BDNF, GABA and Glu of hemiplegic patients

Effects of different modes of transcranial direct current stimulation on rehabilitation and BDNF, GABA and Glu of hemiplegic patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109384
Enrollment
Unknown
Registered
2025-09-17
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral apoplexy

Interventions

Control group:Pseudo-tDCS stimulation
Anode group:Anode tDCS stimulation
Cathode group:Cathode tDCS stimulation
Bilateral group:Bilateral tDCS stimulation

Sponsors

Shaoyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients and their families volunteered to join this study and signed the corresponding informed consent form; 2. Meet the diagnostic criteria of stroke; 3. Motor dysfunction of lower limbs occurred after stroke, and Ashworth scale rated it as Grade 2 or below, and Brunnstrom stage of lower limbs was ? ~ ?; 4. Age ranged from 18 to 80 years; 5. Patients are conscious and can cooperate with relevant training.

Exclusion criteria

Exclusion criteria: 1. There are metallic foreign bodies in the brain or body (such as pacemakers and spinal internal fixators); 2. Skull defect, severe brain edema and increased intracranial pressure; 3. Patients with skin lesions or inflammation at the treatment site. 4. those with unstable vital signs.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer balance function evaluation table;Subjective fatigue rating scale;Brain-derived neurotrophic factor;Y- aminobutyric acid;glutamic acid;

Secondary

MeasureTime frame
Patient satisfaction;MRC rating scale;FAC walking function rating scale;

Countries

China

Contacts

Public ContactPeng Xianying

Shaoyang Central Hospital

804407494@qq.com+86 182 0729 0305

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026