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Palonosetron hydrochloride for the prevention of acute and delayed vomiting in cancer patients undergoing chemotherapy: a real-world study

Palonosetron hydrochloride for the prevention of acute and delayed vomiting in cancer patients undergoing chemotherapy: a real-world study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109367
Enrollment
Unknown
Registered
2025-09-17
Start date
2025-09-22
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer

Interventions

Observation group:None

Sponsors

General Hospital of Xuzhou Mining Group
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years and older with a diagnosis of malignant tumors who are undergoing chemotherapy regimens with a high/medium risk of vomiting; 2. Use of palonosetron hydrochloride as part of the antiemetic regimen; 3. Expected survival duration of 3 months or more; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. The presence of other diseases affecting the assessment of nausea and vomiting (such as gastrointestinal obstruction, brain metastasis, active gastric ulcer, etc.); 2. Use of other antiemetic medications within one week prior to chemotherapy; 3. Pregnant or breastfeeding women; 4. Patients with mental cognitive disorders; 5. Other conditions deemed unsuitable for participation in the study by the investigator.

Design outcomes

Primary

MeasureTime frame
Complete relief rate;

Secondary

MeasureTime frame
Complete control rate;Functional Living Index–Emesis (FLIE) Scores;Frequency of vomiting;The timing and duration of each vomiting episode;The severity of nausea;The emergency medicine used;adverse event;

Countries

China

Contacts

Public ContactBaoqing Wang

General Hospital of Xuzhou Mining Group

13952234612@163.com+86 139 5223 4612

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026