This study did not focus on specific diseases, and the subjects were elderly patients requiring surgical procedures.
Conditions
Interventions
E1 Group:Administer sufentanil 0.1 µg/kg, esketamine 0.45mg/kg, and ciprofol.
E2 Group:Administer sufentanil 0.2 µg/kg, esketamine 0.3 mg/kg, and ciprofol.
E3 Group:Administer sufentanil 0.3µg/kg, esketamine 0.15 mg/kg, and ciprofol.
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Elderly patients, aged 60 to 80 years, with ASA physical status I-III, who underwent surgical procedures at Hainan Provincial People's Hospital between January 2025 and December 2026, were selected.
Exclusion criteria
Exclusion criteria: Patients with any of the following conditions were excluded: intracranial hypertension, impaired consciousness, or severe cardiovascular and cerebrovascular diseases; a history of psychiatric disorders, long-term use of psychotropic or sedative-hypnotic medications; history of drug abuse or alcoholism; difficult airway, hyperreactive airway disease, acute upper respiratory tract infection, or high risk of aspiration; hearing or communication impairments; history of drug allergies; pregnant or lactating women; participation in other clinical trials within the past three months; or unwillingness to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pressure;Heart rate;BIS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time; | — |
Countries
China
Contacts
Public ContactJing Du
Hainan General Hospital
Outcome results
None listed