Spesis
Conditions
Interventions
Index test:ddPCR
Sponsors
Tianjin First Central Hospital
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age should be 14 years or older, and gender is not restricted; 2. Also meet the following requirements: (1) Meet the diagnostic criteria for sepsis: an increase of >= 2 points in the SOFA score or a qSOFA score of >= 2 points (early); Or in During the hospitalization, based on the patient's clinical manifestations and laboratory tests, a high suspicion of bloodstream infection was identified, which met the following conditions: There was a fever (>38?) or hypothermia (10.0×10^9/L) or decreased white blood cell count (<3.0×10^9/L), with systemic infection symptoms and signs such as neutrophil increase accompanied by nuclear left shift, and no other causes could explain it; 3). The systolic blood pressure was lower than 90 mmHg or decreased by more than 40 mmHg; (2). If conditions permit, ddPCR and blood culture tests can be conducted simultaneously.
Exclusion criteria
Exclusion criteria: People with mental disorders, pregnant women, and other special groups.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The sensitivity of digital PCR testing for patients with sepsis;The specificity of digital PCR testing for patients with sepsis; | — |
Countries
China
Contacts
Public ContactWenjie Yang
Tianjin First Central Hospital
Outcome results
None listed