Airway stenosis
Conditions
Interventions
Combination Therapy Group:Nebulized lidocaine (2% solution, 5 ml) plus budesonide (1 mg/2 ml) was administered within 30 minutes before surgery.
Lidocaine Group:Nebulized lidocaine (2% solution, 5 ml) plus normal saline (2 ml) was administered within 30 minutes before surgery.
Control Group:Nebulized normal saline (7 ml) was administered within 30 minutes before surgery.
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. Scheduled to undergo fiberoptic bronchoscopy surgery. 3. ASA physical status classification of II-IV.
Exclusion criteria
Exclusion criteria: 1. Known allergy to lidocaine or budesonide. 2. Severe cardiac, hepatic, or renal dysfunction. 3. Pregnancy or lactation. 4. Recent use of corticosteroid medication. 5. Pre-existing severe psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and severity of post-extubation cough.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative vital signs;The incidence of intraoperative bucking.;The incidence of rescue medication use.;Other intraoperative and postoperative adverse reactions (including airway spasm, hypoxemia, postoperative hoarseness, glottic edema, etc.);The amount of anesthetic drugs used during the operation;Patient operation time, anesthesia time, extubation time, PACU dwell time; | — |
Countries
China
Contacts
Public ContactGangming Wu
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed