Acute respiratory distress syndrome in children
Conditions
Interventions
Group 1 :Do not intervene
Group 2:Do not intervene
Group 3:Do not intervene
Sponsors
Children’s Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ARDS group: 28 days to 16 years old, children with endotracheal intubation who meet the diagnostic criteria for pediatric ARDS; 2. Non-ARDS group: 28 days to 16 years old, endotracheal intubated and ventilated children who do not meet the diagnostic criteria for pediatric ARDS; 3. Healthy group: 28 days to 16 years old, healthy children who come to the Department of Pediatrics of our hospital for health check-up, no hospitalization in the last 2 months, no respiratory diseases, no oral antibiotic drugs, no chronic diseases such as epilepsy, immunodeficiency and arrhythmia
Exclusion criteria
Exclusion criteria: Severe malnutrition, colostomy or ileostomy, gastrointestinal surgery in the past 1 month, long-term oral immunosuppressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines;Microbial community composition;Metabolite profile;Ventilator ventilation time;Oxygenation index;survive;death;Respiratory failure;Fibrinogen;Lymphocyte absolute count; | — |
Secondary
| Measure | Time frame |
|---|---|
| C reactive protein;B-type brain natriuretic peptide;pediatric sequential organ failure score;prothrombin time;D-dimer;activated partial thromboplastin time, APTT;Hemoglobin;platelet;total white blood cells;Procalcitonin;Alanine aminotransferase;lactate dehydrogenase;creatinine;Myocardial markers; | — |
Countries
China
Contacts
Public ContactFu Yueqiang
Children’s Hospital of Chongqing Medical University
Outcome results
None listed