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Association of dual-energy CT parameters in the low-density component of Carotid Plaque and Ipsilateral Ischemic Acute Stroke

Quantitative assessment of carotid plaque composition based on energy-spectrum CT and its clinical application value

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109290
Enrollment
Unknown
Registered
2025-09-16
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Case series:NA

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with carotid plaques who underwent dual-energy CTA and healthy controls without plaques; more complete clinical examination data (e.g., lipids, glucose, homocysteine, etc.); and clear clinical manifestations (e.g., with or without history of stroke or TIA).

Exclusion criteria

Exclusion criteria: Other serious comorbidities affecting the study analysis (e.g. acute inflammatory disease, malignancy); poor image quality or inability to perform dual-energy parametric analysis; and those with missing clinical data.

Design outcomes

Primary

MeasureTime frame
Zeff;vascular stenosis degree;—

Secondary

MeasureTime frame
iodine concentration;slope of the spectral curve (k);Fat volume fraction;maximum plaque thickness;maximum plaque thickness of the?non-calcified portion;plaque length;—

Countries

China

Contacts

Public ContactJing Zhang

Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

tjh_jingzhang@hust.edu.cn+86 181 6407 3997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026