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Effect of quantium noxious index (qNOX) monitoring on perioperative opioid consumption and postoperative recovery in elderly patients undergoing colorectal surgery

Effect of quantium noxious index (qNOX) monitoring on perioperative opioid consumption and postoperative recovery in elderly patients undergoing colorectal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109275
Enrollment
Unknown
Registered
2025-09-16
Start date
2025-09-20
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain

Interventions

Test group (Group N):Receive monitoring of the injury index qNOX and receive guidance, and adjust the analgesic dose according to the number shown
Control group (Group D):The qNOX index is not visible and does not accept the guidance of the qNOX index. The analgesic dose is adjusted only based on one's own clinical expe

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1: Age: Elderly patients aged 65-90, male and female, no limit; 2: ASA classification of the American Academy of Anesthesiologists: Grades I-III; 3: Laparoscopic colorectal surgery under general anesthesia; 4: the estimated operation time is more than 60 minutes, and the postoperative transfer to PACU; 5: comply with this test procedure and voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1: Patients who cannot obtain informed consent; 2: emergency surgery; 3: non-general anesthesia surgery; 4: patients who are known to be allergic to or intolerant to anesthetic drugs; 5: acute or chronic pain before surgery or a long-term use of opioid or non-opioid pain medications; 6: peripheral or central nervous system disorders; 7: clear history of diagnosed mental illness or other history of neurological or mental illness that affects the judgment of severe cognitive impairment, and history of psychotropic drugs; 8: basal mean arterial pressure (MAP) is less than 60 mmHg or greater than 120 mmHg, basal heart rate (HR) is less than 45 beats/minute or greater than 120 mmHg; 9: history of severe underlying diseases, such as untreated or persistent peripheral or central cardiovascular disease, severe liver or renal disease, and severe pulmonary disease.

Design outcomes

Primary

MeasureTime frame
Opioid consumption;

Secondary

MeasureTime frame
VAS Pain Score;Time to remove the tracheal catheter;PACU stay time;Hospitalization time;Intestinal function recovery assessment;blood pressure;heart rate;Blood sugar;Lactic acid;

Countries

China

Contacts

Public ContactYunsheng Li

The First Affiliated Hospital of Sun Yat-sen University

liysheng@mail.sysu.edu.cn+86 137 6086 3235

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026