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Observation of the efficacy of quadriceps strength exercise combined with subpatellar fat pad injection hormone injection in the treatment of osteoarthritis

Observation of the efficacy of quadriceps strength exercise combined with subpatellar fat pad injection hormone injection in the treatment of osteoarthritis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109267
Enrollment
Unknown
Registered
2025-09-16
Start date
2025-09-20
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild to moderate knee osteoarthritis

Interventions

Group B (Quadriceps Strength Training Group):Quadriceps strength training
Group A (Hormone Injection Group):Hormone injection into the infrapatellar fat pad
Group C (Combined Treatment Group):Quadriceps strength trainingHormone injection into the infrapatellar fat pad

Sponsors

Hefei First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 40 years old or above; 2. Radiological confirmation of clinically diagnosed tibiofemoral arthritis; 3. Clinical symptoms of local knee joint inflammation; 4. Knee pain while walking (score of 0-10 > 4); 5. BMI <= 35.

Exclusion criteria

Exclusion criteria: 1. Potential participants who have received steroid injections or participated in exercise therapy in the past 3 months; 2. Individuals who have used oral corticosteroids or have inflammatory arthritis in the past 4 weeks; 3. History of knee replacement surgery; 4. Conditions that exclude participation in exercises; 5. Contraindications for corticosteroids; 6. Local pain syndromes (e.g., fibromyalgia); 7. Participants with spinal nerve root compression syndromes.

Design outcomes

Primary

MeasureTime frame
WOMAC Functional Score;

Secondary

MeasureTime frame
K-L grading;

Countries

China

Contacts

Public ContactRende Ning

Hefei First People's Hospital

nrd1972@outlook.com+86 551 82137855

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026