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To explore the relationship between preoperative sleep disorders and postoperative delirium in elderly patients based on IGF-1

To explore the relationship between preoperative sleep disorders and postoperative delirium in elderly patients based on IGF-1

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109251
Enrollment
Unknown
Registered
2025-09-16
Start date
2025-05-07
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Sleep Disorder Group (Group A, PSQI > 5):None (Observational studies do not involve intervention measures)
Normal Sleep Group (Group N, PSQI <= 5):None (Observational studies do not involve intervention measures)

Sponsors

Department of Anesthesiology, Navy Medical Center of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Elderly patients (aged >= 60 years) scheduled for non-cardiac surgery under elective general anesthesia; 2. The Pittsburgh Sleep Quality Index (PSQI) score can be conducted the day before the operation; 3. Delirium assessment (CAM scale) can be conducted for at least 3 consecutive days after the operation; 4. Sign the informed consent form and voluntarily participate in the research.

Exclusion criteria

Exclusion criteria: 1. There is a clear history of mental or neurological disorders (such as dementia, Parkinson's disease, etc.) before the operation; 2. Those who have been using sedative-hypnotic drugs or antipsychotic drugs for a long time; 3. Combined with severe visual or hearing impairment, affecting postoperative assessment; 4. Major complications occur during or after the operation, affecting the follow-up of the study.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium occurrence;

Secondary

MeasureTime frame
Preoperative sleep quality score;Preoperative IGF-1 levels;

Countries

China

Contacts

Public ContactWang Chen

The Navy Specialized Medical Center of the People's Liberation Army of China

wangchen_ntu@163.com+86 153 1093 6065

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026