Sepsis-related cardiac dysfunction
Conditions
Interventions
Control group:(0.9% NS 100ML) Sodium Chloride Injection
Sponsors
Jiangsu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.It also meets the diagnostic criteria for sepsis and heart failure. 2.Traditional Chinese medicine distinguishes as qi deficiency and blood stasis. 3.Age 18~80 years old. 4.Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those under the age of 18 or over 80, or pregnant or lactating women. 2.Patients with irreversible underlying diseases or expected death within 48 hours, such as advanced malignant tumors, extremely severe head injury, etc. 3.Allergic constitution, or known to be allergic to the ingredients of this medicine. 4.Patients who have given up rescue and cannot undergo conventional Western medicine and basic vital signs support therapy. 5.Those who do not meet the inclusion criteria, do not use and treat as prescribed, or have incomplete data that affect the efficacy or safety judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left Ventricular Ejection Fractions;Cardiac Index;Fractional shortening;Left Ventricular End-diastolic Dimension;E/A;E/e';Lactate;Central Venous Oxygen Saturation;Pv-aCO2;Urine output; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain Natriuretic Peptide;Cardiac Troponin I;Endocan;Vascular Endothelial Growth Factor;Endothelin-1;Soluble Thrombomodulin;Tumornecrosisfactor-a;Interleukin-1ß;Complement C5a;Sequential organ failure;Acute physiology and chronic health evaluation II;Time of mechanical ventilation;Length of ICU stay;ICU case fatality rate;28-day case fatality rate; | — |
Countries
China
Contacts
Public ContactGuo Tao
Jiangsu Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed