Interstitial lung disease requiring pathological biopsy, with patients with small pulmonary nodules as controls
Conditions
Interventions
observation group:None
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age greater >=18 years old, regardless of gender. 2.According to ICH-GCP and local laws, sign and date an informed consent form before initiating any research related procedures during screening visits. 3.Patients diagnosed with interstitial lung disease through MDD who require frozen lung biopsy for further clarification of the diagnosis. 4.Can tolerate bronchoscopy under general anesthesia without any allergic reactions to anesthetic drugs. 5.Contraindications for non bronchoscopy examination. 6. patients who have never smoked or have quit smoking for more than 3 months. 7. patients who have not been diagnosed with acute exacerbations by researchers. 8.Patients who require bronchoscopy due to small pulmonary nodules as a control group. 9.Good compliance, willing to conduct inspections and follow up on time according to the requirements of the plan. 10.The subjects were informed of the research purpose, methods, and potential discomfort and risks, agreed to participate in the trial, and signed an informed consent form. 11.The researchers evaluated and approved the participants for inclusion.
Exclusion criteria
Exclusion criteria: 1.Individuals with contraindications for bronchoscopy examination. 2.Patients who are in the acute exacerbation phase on the day of screening or enrollment. 3.Screening includes patients who were infected on the day of enrollment, including those with bacterial, viral, fungal, or tuberculosis infections. 4.Pregnant women. 5.Individuals with mental illnesses who cannot be followed up on schedule. 6.After review by the researchers, it was deemed unsuitable for inclusion. 7.Patients who are unable to sign informed consent forms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in sensitivity between CLE and HRCT in diagnosing ILD;Differences in specificity between CLE and HRCT in diagnosing ILD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Characteristics of ILD and CLE in normal patients;The safety of CLE in bronchoscopy examination of ILD patients; | — |
Countries
China
Contacts
Public ContactLi qiuhong
Shanghai Pulmonary Hospital
Outcome results
None listed